FITC Anti-Mouse FcεRIα Antibody[MAR-1]
Catalogue Number: E-AB-F1188UC-ELA
E-AB-F1188UC Image
E-AB-F1188UC Image
E-AB-F1188UC Image
C57BL/6 murine bone marrow cells are stained with APC Anti-Mouse CD49b Antibody and FITC Anti-Mouse FcεRIα Antibody (Left). Bone marrow cells stained with APC Anti-Mouse CD49b Antibody and FITC Armenian Hamster IgG Isotype Control (Right) are used as control.
E-AB-F1188UC Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | Fc-epsilon RI-alpha;FcERI;Fcer1a;High affinity immunoglobulin epsilon receptor subunit alpha |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Armenian Hamster |
| Clone: | MAR-1 |
| Isotype: | IgG |
| Immunogen: | |
| Application: | FC |
Description
Description: FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.
Additional Text
Gene Name
FCER1A
Gene ID
14125
Concentration
0.5 mg/ml
Uniprot ID
P20489
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1188UC MSDS
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