FITC Anti-Mouse CD366/Tim-3 Antibody[RMT3-23]
Catalogue Number: E-AB-F1192UC-ELA
E-AB-F1192UC Image
E-AB-F1192UC Image
E-AB-F1192UC Image
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Anti-Mouse CD366/Tim-3 Antibody (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and FITC Rat IgG2a, κ Isotype Control (Right).
E-AB-F1192UC Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | TIMD3;HAVcr-2;TIM3;TIMD-3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ug, 25 ug |
| Host name: | Rat |
| Clone: | RMT3-23 |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD366 (Tim-3) is a transmembrane protein also known as T cell immunoglobulin and mucin domain containing protein-3. Tim-3 is expressed at high levels on activated T cells (preferentially on Th1 cells, monocytes/macrophages, and dendritic cells). Tim-3 has also been shown to exist as a soluble protein. Cells expressing Tim-3 are present at high levels in the CNS of animals at the onset of experimental autoimmune encephalomyelitis (EAE), a disease mediated by lymphocytes secreting Th1-like cytokines. Tim-3 has been proposed to inhibit Th1-mediated immune responses and promote immunological tolerance.
Additional Text
Concentration
0.5 mg/ml
Uniprot ID
Q8VIM0
Antibody Clonality
Monoclonal
Gene ID
171285; 84868
Gene Name
Havcr2, HAVCR2
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1192UC MSDS
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