AF/LE Purified Anti-Human CD28 Antibody[CD28.2]
Catalogue Number: E-AB-F11950-ELA
| Manufacturer: | Elabscience |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | PAS2;MNS;HGpMiX;GYPA;GPSAT |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 mg, 100 ug, 25 mg, 25 ug, 5 mg, 50 mg |
| Host name: | Mouse |
| Clone: | CD28.2 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, Act |
Description
Description: CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
Additional Text
Gene ID
940
Gene Name
CD28
Uniprot ID
P10747
Antibody Clonality
Monoclonal
Concentration
>=1 mg/ml
Storage Note
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
E-AB-F11950 MSDS
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