AF/LE Purified Anti-Human CD11a Antibody[R7-1]

Catalogue Number: E-AB-F12110-ELA

Manufacturer:Elabscience
Type:Monoclonal Primary Antibody - Unconjugated
Alias:Integrin alpha-L;LFA-1A;CD11A;ITGAL
Shipping Condition:Blue Ice
Unit(s): 1 mg, 100 mg, 100 ug, 25 mg, 25 ug, 5 mg, 50 mg
Host name: Mouse
Clone: R7-1
Isotype: IgG1, kappa
Immunogen:
Application: FC, FA

Description

Description: CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Additional Text

Gene Name

Itgal

Gene ID

3683

Uniprot ID

P20701

Antibody Clonality

Monoclonal

Concentration

>=1 mg/ml

Storage Note

Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Price
£163.00


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