Elab Fluor® Violet 450 Anti-Rat CD45 Antibody[OX-1]

Catalogue Number: E-AB-F1227UQ-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:LCALy-5T200;Leukocyte common antigen;Ptprc;Receptor-type tyrosine-protein phosphatase C
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Mouse
Clone: OX-1
Isotype: IgG1, kappa
Immunogen:
Application: FC

Description

Description: CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Additional Text

Concentration

0.5 mg/ml

Uniprot ID

P04157

Antibody Clonality

Monoclonal

Gene ID

19265; 24699

Gene Name

Ptprc, Ptprcap

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.