PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody[EH12.2H7]
Catalogue Number: E-AB-F1229J-ELA
E-AB-F1229J Image
E-AB-F1229J Image
E-AB-F1229J Image
MOLT-4 cells treated with 500 ng/ml Ionomycin and 10 ng/ml Phorbol-12-myristate-13-acetate (PMA) for 24 hours are stained with PerCP/Cyanine5.5 Anti-Human CD279/PD-1 Antibody (filled gray histogram) or PerCP/Cyanine5.5 Mouse IgG1, κ Isotype Control (empty black histogram).
E-AB-F1229J Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | PD1;PDCD1;Protein PD-1;hPD-1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 20 tests, 200 tests |
| Host name: | Mouse |
| Clone: | EH12.2H7 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: Programmed cell death 1 (PD-1), also known as CD279, is a 55 kD member of the immunoglobulin superfamily. CD279 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) in the cytoplasmic region and plays a key role in peripheral tolerance and autoimmune disease. CD279 is expressed predominantly on activated T cells, B cells, and myeloid cells. PD-L1 and PD-L2 are ligands of CD279 (PD-1) and are members of the B7 gene family. Evidence suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells. Interaction of CD279 ligands results in inhibition of T cell proliferation and cytokine secretion.
Additional Text
Gene Name
PDCD1
Gene ID
5133
Uniprot ID
Q15116
Concentration
5 ul/test
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1229J MSDS
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