AF/LE Purified Anti-Human CD16 Antibody[3G8]
Catalogue Number: E-AB-F12360-ELA
| Manufacturer: | Elabscience |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Alias: | FcγRIII;Fc gamma receptor;Fc gamma receptor 3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 1 mg, 100 mg, 100 ug, 25 mg, 25 ug, 5 mg, 50 mg |
| Host name: | Mouse |
| Clone: | 3G8 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC, Blk |
Description
Description: CD16 is a 60 kD highly glycosylated protein. It is a member of the Ig superfamily and is also known as B7-1, B7, and Ly-53. CD16 is constitutively expressed on dendritic cells and monocytes/macrophages, and inducibly expressed on activated B and T cells. The ligation of CD28 on T cells with CD16 and CD86 (B7-2) on antigen presenting cells (such as dendritic cells, macrophages, and B cells) elicits co-stimulation of T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD16 appears to be expressed later in the immune response than CD86. CD16 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.
Additional Text
Uniprot ID
O75015, P08637
Antibody Clonality
Monoclonal
Concentration
>=1 mg/ml
Gene ID
2214; 2215; 941
Gene Name
CD80, FCGR3A, FCGR3B
Storage Note
Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
SUPPORT
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PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations