Elab Fluor® 488 Anti-Mouse CD107a/LAMP-1 Antibody[1D4B]
Catalogue Number: E-AB-F1254L-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD107 antigen-like family member Alysosomal membrane glycoprotein 1lysosome-associated membrane protein 1;LAMP-1;Lysosome-associated membrane glycoprotein 1 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 200 tests, 50 tests |
| Host name: | Rat |
| Clone: | 1D4B |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: The 1D4B antibody recognizes CD107a which is also known as, Lysosome-Associated Membrane Protein 1 (LAMP-1). CD107a is one of the two major glycoproteins in lysosome membranes that provide useful markers to distinguish lysosomes from other organelles. CD107a may play a role in the lysosomal degradation of certain molecules. Mouse CD107a is a type I transmembrane glycoprotein. It consists of a 40-kDa core protein which is heavily glycosylated to form heterogeneous mature glycoprotein of 110-140 kDa. It is principally expressed in epithelial cells and macrophages in a variety of organs. Following activation, CD107a is relocated to the surface of some lymphocytes, macrophages, epithelial cells, endothelial cells, platelets, and tumor cells. Cell-surface CD107a may participate in intercellular adhesion and adhesion to the extracellular matrix. Cell surface CD107a expression can serve as a useful marker for cytotoxic NK and CD8+ T cells, as well as, some malignant tumor cells.
Additional Text
Gene Name
LAMP1
Gene ID
16783
Concentration
5 ul/test
Uniprot ID
P11438
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1254L MSDS
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