Elab Fluor® 647 Anti-Mouse CD163 Antibody[S15049F]

Catalogue Number: E-AB-F1295UM-ELA

Manufacturer:Elabscience
Shelf Life:12 months
Type:Monoclonal Primary Antibody - Conjugated
Alias:MM130SCARI1;M130
Shipping Condition:Blue Ice
Unit(s): 100 ug, 25 ug
Host name: Rat
Clone: S15049F
Isotype: IgG2a, kappa
Immunogen:
Application: FC

Description

Description: CD163 is a member of the group B scavenger receptor cysteine-rich superfamily, also known as GHI/61, M130, RM3/1, p155, hemoglobin-haptoglobin complex receptor, or macrophage-associated antigen. It is a 134 kD (non-reduced)/155 kD (reduced) glycoprotein primarily expressed on macrophages, Kupffer cells, monocytes, a subset of dendritic cells, and a subset of hematopoietic stem/progenitor cells. CD163 binds to haptoglobin-hemoglobin complex and TWEAK, and plays a role in clearing hemoglobin and regulating cytokine production by macrophages. Membrane CD163 can be cleaved by metalloproteinases (MMP), resulting in a soluble form. Elevated serum level of sCD163 has been implicated in many kinds of inflammatory diseases.

Additional Text

Gene Name

CD163

Uniprot ID

Q2VLH6

Concentration

0.5 mg/ml

Gene ID

93671

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.