Elab Fluor® Violet 450 Anti-Human CD193/CCR3 Antibody[5E8]

Catalogue Number: E-AB-F1303Q-ELA

Manufacturer:	Elabscience
Shelf Life:	12 months
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	MIP1-alpha receptor like-2eotaxin receptor;C-C chemokine receptor type 3;CC CKR3;CCR
Shipping Condition:	Blue Ice
Unit(s):	100 tests, 2 x 100 tests, 20 tests
Host name:	Mouse
Clone:	5E8
Isotype:	IgG2b, kappa
Immunogen:
Application:	FC

Overview
Datasheets

Description

Description: CD193, also known as CC-chemokine receptor 3 (CCR3), CC CKR3, MIP1-alpha receptor like-2, and eotaxin receptor, is a member of the G protein-coupled seven transmembrane receptors family. It binds to the CC chemokines eotaxin, eotaxin-2, and eotaxin-3 with high affinity. CCR3 has also been reported to bind RANTES, MCP-3, and MCP-4 with low affinity. CCR3 receptor is expressed on human eosinophils, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2-like lymphocytes, and keratinocytes. CCR3 is thought to play a role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV-1 and HIV-2, and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types.

Additional Text

Gene Name

CCR3

Uniprot ID

P51677

Gene ID

1232

Concentration

5 ul/test

Antibody Clonality

Monoclonal

Storage Note

This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

E-AB-F1303Q MSDS

E-AB-F1303Q Datasheet

Price

£238.00

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