PE/Elab Fluor® 594 Anti-Mouse/Rat Foxp3 Antibody[FJK-16s]
Catalogue Number: E-AB-F1351P-ELA
E-AB-F1351P Image
E-AB-F1351P Image
E-AB-F1351P Image
C57BL/6 murine splenocytes are stained with APC Anti-Mouse CD4 Antibody and PE/Elab Fluor® 594 Anti-Mouse/Rat FOXP3 Antibody[FJK-16s] (Left). Splenocytes are stained with APC Anti-Mouse CD4 Antibody and PE/Elab Fluor® 594 Rat IgG2a, κ Isotype Control (Right).
E-AB-F1351P Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | IPEXJM2ScurfinZinc finger protein JM2;Forkhead box protein P3 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 2 x 100 tests, 50 tests |
| Host name: | Rat |
| Clone: | FJK-16s |
| Isotype: | IgG2a, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: FOXP3 is a 47 kD transcription factor, also known as Forkhead box protein P3, Scurfin, JM2, or IPEX. It is proposed to be a master regulatory gene and more specific marker of T regulatory cells than most cell surface markers (such as CD4 and CD25). Transduced expression of FOXP3 in CD4+/CD25- cells has been shown to induce GITR, CD103, and CTLA4 and impart a T regulatory cell phenotype. FOXP3 is mutated in X-linked autoimmunity-allergic dysregulation syndrome (XLAAD or IPEX) in humans and in "scurfy" mice. Overexpression of FOXP3 has been shown to lead to a hypoactive immune state suggesting that this transcriptional factor is a central regulator of T cell activity.
Additional Text
Gene Name
FOXP3
Gene ID
20371
Uniprot ID
Q99JB6
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1351P MSDS
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