PE/Cyanine5 Anti-Human CD244 Antibody[C1.7]
Catalogue Number: E-AB-F1374G-ELA
E-AB-F1374G Image
E-AB-F1374G Image
E-AB-F1374G Image
Staining of normal human peripheral blood cells with FITC Anti-Human CD8a Antibody[OKT-8] and PE/Cyanine5 Anti-Human CD244 Antibody[C1.7] (left) or PE/Cyanine5 Mouse IgG1, κ Isotype Control (right). Cells in the lymphocytes gate were used for analysis.
E-AB-F1374G Image
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | 2B4;SLAMF4 |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests, 2 x 100 tests, 20 tests |
| Host name: | Mouse |
| Clone: | C1.7 |
| Isotype: | IgG1, kappa |
| Immunogen: | |
| Application: | FC |
Description
Description: CD244, known as 2B4, is a 38 kD type I transmembrane protein. It is a member of the CD2 subset of the immunoglobulin superfamily (IgSF) molecules. CD244 is expressed on NK cells, a subset of T cells (including most CD8+ T cells and γ/δ T cells), monocytes, basophils, and eosinophils. CD48 is the ligand of CD244. It has been reported that ligation of human CD244 results in enhanced NK cell cytotoxicity and cytokine production. Recent studies have shown that human CD244, like murine CD244, has both activating and inhibitory functions, which are dependent on the density of surface 2B4 expression, degree of ligation, and the level of the adaptor molecule SAP expression.
Additional Text
Uniprot ID
Q9BZW8
Gene Name
CD244
Gene ID
51744
Concentration
5 ul/test
Antibody Clonality
Monoclonal
Storage Note
This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
E-AB-F1374G MSDS
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