SARS-CoV-2 E Protein Polyclonal Antibody(2019-nCoV)
Catalogue Number: E-AB-V1033-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | 2019-nCoV E protein;2019-nCoV sM protein;Envelope small membrane protein |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant SARS-CoV-2 E protein |
| Application: | ELISA |
Description
Description: Coronavirus envelope (E) proteins are short (100 residues) polypeptides that contain at least one transmembrane (TM) domain and a cluster of 2-3 juxtamembrane cysteines. These proteins are involved in viral morphogenesis and tropism, and their absence leads in some cases to aberrant virions, or to viral attenuation. In common to other viroporins, coronavirus envelope proteins increase membrane permeability to ions, plays a central role in virus morphogenesis and assembly. Acts as a viroporin and self-assembles in host membranes forming pentameric protein-lipid pores that allow ion transport. Also plays a role in the induction of apoptosis. Activates the host NLRP3 inflammasome, leading to IL-1beta overproduction.
Additional Text
Concentration
0.3 mg/ml
Antibody Clonality
Polyclonal
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-V1033 Protocol
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations