SARS-CoV-2 NSP8 Polyclonal Antibody(2019-nCoV)
Catalogue Number: E-AB-V1041-ELA
| Manufacturer: | Elabscience |
| Shelf Life: | 12 months |
| Preservative: | 0.05% ProClin™ 300 |
| Type: | Polyclonal Primary Antibody - Unconjugated |
| Alias: | Non-structural protein 8;Replicase polyprotein 1a |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul, 50 ul |
| Host name: | Rabbit |
| Clone: | |
| Isotype: | IgG |
| Immunogen: | Recombinant SARS-CoV-2 NSP8 |
| Application: | ELISA |
Description
Description: Cleavage by the viral main protease, 3CLpro results in generating the nsp8 protein, The nsp8 protein has been shown to associate with several other nsps and to colocalize with these nsps in cytoplasmic complexes that are important for viral RNA synthesis. It forms a hexadecamer with nsp7 (8 subunits of each) that may participate in viral replication by acting as a primase. Alternatively, may synthesize substantially longer products than oligonucleotide primers. Nsp8 was shown to have RNA-dependent RNA polymerase (RdRp) activity that could be involved in producing primers utilized by nsp12 which is normally accepted to be the RdRp for SARS-CoV.
Additional Text
Concentration
0.93 mg/ml
Antibody Clonality
Polyclonal
Storage Note
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
E-AB-V1041 Protocol
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