E2F1 Transcription Factor (E2F 1, Retinoblastoma associated protein 1, Retinoblastoma binding protein 3, PBR3, RBAP-1, RBBP3, RBP3) (MaxLight 650)

Catalogue Number: E0010-ML650-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	E2F-1\|PBR3\|PRB-binding protein E2F-1\|RBAP1\|RBAP-1\|RBBP3\|RBBP-3\|RBP3\|retinoblastoma-associated protein 1\|retinoblastoma-binding protein 3\|transcription factor E2F1
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	KH20 and KH95
Isotype:	IgG
Immunogen:	GST fusion protein corresponding to full-length human E2F-1. Epitope: aa1-89 for clone KH20; aa342-386 for clone KH95.
Application:	IP, WB

Overview
Datasheets

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. E2F-1 was identified as a cellular protein with DNA binding activity associated with the adenovirus E2 gene promoter. The original member of the E2F family of transcription factors, now consisting of five, was identified through its association with the retinoblastoma protein, which controls its activity. E2F-1 is cell cycle regulated with very low levels in early G1 then increasing levels as cells move from G1 to S with highest levels of protein at the G1/S boundary, which is consistent with its role in S-phase entry.

Additional Text

Gene Name

E2F1

Gene ID

1869

Uniprot ID

Q01094

Accession Number

NP_005216

Specificity

Recognizes human E2F-1 at ~55kD. Species Crossreactivity: Xenopus

Purification

Protein G purified

Antibody Clonality

Monoclonal

E0010-ML650 Datasheet

Price

£979.00

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Quantity
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