Pseudolaric Acid A
Catalogue Number: E0249-SEL
| Manufacturer: | Selleck Chemicals |
| Type: | Biochemicals |
| Shipping Condition: | Blue Ice |
| Unit(s): | 5 mg |
Description
Description: Pseudolaric acid A, a Hsp90 inhibitor with an IC50 of 0.60 µM, 2.72 µM, 1.36 µM, 2.92 µM and 6.16 µM in HL-60, A549, SMMC-7721, HeLa and SW480 cells respectively, is the main bioactive ingredient in Pseudolarix cortex, and induces cell cycle arrest at G2/M phase and promotes cell death through caspase-8/caspase-3 pathway, demonstrating potent antiproliferation and anticancer activities.
Inhibitor Handling Instructions
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