Masitinib mesylate

Catalogue Number: E0814-SEL

Manufacturer:Selleck Chemicals
Shelf Life:36 months
Molecular Formula:C28H30N6OS.CH4O3S
Type:Other Proteins
Alias:AB-1010 mesylate
Shipping Condition:Blue Ice
Unit(s): 25 mg

Additional Text

CAS Number

1048007-93-7

Short Description

Masitinib mesylate (AB-1010 mesylate) is a potent, orally bioavailable, and selective inhibitor of c-Kit with IC50 of 200 nM for human recombinant c-Kit, also inhibits PDGFRα/β with IC50s of 540/800 nM, Lyn with IC50 of 510 nM for LynB, and, to a lesser extent, FGFR3 and FAK.

Smile String

CN1CCN(CC1)CC2=CC=C(C=C2)C(=O)NC3=CC=C(C)C(=C3)NC4=NC(=CS4)C5=CN=CC=C5.C[S](O)(=O)=O

Storage Note

3 years -20°C powder