CHD1Li 6.11
Catalogue Number: E1146-SEL
| Manufacturer: | Selleck Chemicals |
| Shelf Life: | 36 months |
| Molecular Formula: | C21H22BrN5OS |
| Type: | Other Proteins |
| Shipping Condition: | Blue Ice |
| Unit(s): | 25 mg, 5 mg |
Additional Text
CAS Number
2716890-91-2
Smile String
CC1=CC(=NC(=N1)N2CCCC2)NC3=CC=C(NC(=O)CC4=CC(=CS4)Br)C=C3
Short Description
CHD1Li 6.11, a potent oncogenic chromodomain helicase DNA binding protein 1 like (CHD1L) inhibitor and an orally bioavailable antitumor agent, shows the enzymatic inhibition of the catalytic CHD1L (cat-CHD1L) recombinant protein with IC50 of 3.3 µM, and significantly reduces the tumor volume of colorectal cancer (CRC) xenografts generated from isolated quasi mesenchymal cells (M-Phenotype).
Storage Note
3 years -20°C powder
Inhibitor Handling Instructions
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