Endothelin 1 (MaxLight 490)
Catalogue Number: E3098-29B-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | ARCND3|endothelin-1|ET1|HDLCQ7|PPET1|preproendothelin-1|QME |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 2Q2188 |
| Isotype: | IgG1 |
| Immunogen: | |
| Application: | RIA, IHC |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Endothelins (ET) show potent constrictor activity in vascular and non-vascular smooth muscle. This family of 21-amino acid peptides exists in at least three isoforms, ET-1, ET-2, and ET-3, and is produced in endothelial and epithelial cells. ET's can mediate biological effects in cells and tissues, and have been shown to bind to an ET receptor in the lung, kidney, heart and liver.
Additional Text
Uniprot ID
P05305
Gene Name
EDN1
Gene ID
1906
Specificity
Recognizes human endothelin ET-1 (10% crossreactivity with ET-3) and when used in conjunction with anti-endothelin, C-terminal, has a sensitivity of 0.06pmol/l for ET-1.
Purification
Protein A purified
Accession Number
NM_001955.3
Antibody Clonality
Monoclonal
E3098-29B-ML490 Datasheet
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