Rigosertib

Catalogue Number: E7073-SEL

Manufacturer:Selleck Chemicals
Shelf Life:36 months
Type:Other Inhibitors
Alias:ON-191
Shipping Condition:Blue Ice
Unit(s): 5 mg

Additional Text

Short Description

Rigosertib (ON-01910) is a multi-kinase inhibitor and a selective anti-cancer agent, which induces apoptosis by inhibition the PI3 kinase/Akt pathway, promots the phosphorylation of histone H2AX and induces G2/M arrest in cell cycle. Rigosertib is a selective and non-ATP-competitive inhibitor of PLK1 with an IC50 of 9 nM.

Storage Note

3 years-20°C powder 2 years-80°C in solvent