BS-181

Catalogue Number: E7095-SEL

Manufacturer:Selleck Chemicals
Shelf Life:36 months
Type:Other Inhibitors
Shipping Condition:Blue Ice
Unit(s): 5 mg

Additional Text

Short Description

BS-181 is a potent and selective CDK7 inhibitor (IC50=21 nM) than Seliciclib (HY-30237). BS-181 is also against CDK2, CDK5 and CDK9 with IC50 values of 880, 3000 and 4200 nM, respectively (fails to block CDK1, 4 and 6). BS-181 inhibits a panel of cancer cells growth (IC50=11.5 µM-37.3 µM) and induces cell apoptosis. BS-181 has the potential for the research of cancer therapy.

Storage Note

3 years-20°C powder 2 years-80°C in solvent