C16-Ceramide

Catalogue Number: E7154-SEL

Manufacturer:	Selleck Chemicals
Molecular Formula:	C34H67NO3
Type:	Ceramides
Alias:	N-Palmitoylsphingosine
Shipping Condition:	Blue Ice
Unit(s):	5 mg

Overview
Datasheets

Additional Text

Short Description

C16-Ceramide is a sphingolipid ligand and an activator of p53 tumor suppressor. It tightly binds within the p53 DNA-binding domain with a Kd of ~ 60 nM, in close vicinity to the Box V motif. It regulates the protein ubiquitination and proteasomal degradation and also induces apoptosis in cancer cells making it a research tool for targeting human cancers.

E7154 MSDS