Factor VIIIc (Coagulation Factor VIII Isoform c, Coagulation Factor VIIIc, FVIIIc, F8c, F8 Protein, Antihemophilic Factor, AHF, Dxs1253e, HEMA, Procoagulant Component) (MaxLight 490)

Catalogue Number: F0016-29-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Type:Monoclonal Primary Antibody - Conjugated
Alias:AHF|antihemophilic factor|coagulation factor VIII|coagulation factor VIII A1 domain|coagulation factor VIII C2 domain|coagulation factor VIII, procoagulant component|coagulation factor VIIIc|DXS1253E|F8B|F8C|factor VIII F8B|FVIII|HEMA
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 10C188 (2A5)
Isotype: IgG2a
Immunogen: Purified human Factor VIII
Application: FLISA

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Factor VIII is a large glycoprotein (320kD) that circulates in plasma. Synthesized in the liver, the majority of Factor VIII is cleaved during expression, resulting in a heterogeneous mixture of partially cleaved forms of F.VIII. FVIII is a pro-factor that is activated through limited proteolysis by thrombin.

Additional Text

Gene Name

F8

Uniprot ID

P00451

Gene ID

2157

Specificity

Recognizes the light chain of human Factor VIII at 83kD. Does not react with Von Willebrand factor.

Purification

Protein A purified

Antibody Clonality

Monoclonal