FAK (Focal Adhesion Associated Protein Tyrosine Kinase, BC3) (Agarose)

Catalogue Number: F0019-55B-USB

Manufacturer:	United States Biological
Physical state:	Covalently linked to 200ml of protein G agarose beads and provided as a 50% gel slurry suspended in PBS, 0.05% sodium azide for a total volume of 400ml. Liquid suspension.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	200 ug
Host name:	Mouse
Clone:	4.47
Isotype:	IgG1
Immunogen:	GST fusion protein corresponding to residues 1-423 of human FAK.
Application:	IP

Overview
Datasheets

Description

Description: This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. At least four transcript variants encoding four different isoforms have been found for this gene, but the full-length natures of only two of them have been determined.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

PTK2

Gene ID

5747

Uniprot ID

Q05397

Specificity

Recognizes human FAK (Focal Adhesion Associated Protein Tyrosine Kinase, BC3).

Purification

Purified

Accession Number

NM_005607.3

Antibody Clonality

Monoclonal

F0019-55B Datasheet

Price

£857.00

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