Fas (CD95, APO-1) (PE/CY5)

Catalogue Number: F0019-59Z5-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, 0.09% sodium azide and a stabilizing agent. Labeled with PE/CY5.
Type:Monoclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 Tests
Host name: Mouse
Clone: 5K226 (DX3)
Isotype: IgG2a, kappa
Immunogen: Human CD95 transfected L cells
Application: FC, IHC, FLISA

Description

Description: CD95, also known as Fas and Apo-1, is a 40-50kD type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance. PE/CY5 combination conjugate is used as a third fluorochrome in multicolor flow cytometry applications when only a single 488nm excitation source is available. Antibodies are covalently coupled using heterobifunctional linking reagents, resulting in an optimal conjugation format for flow cytometry.

Additional Text

Caution

FOR RESEARCH USE ONLY

Gene Name

FAS

Gene ID

355

Uniprot ID

P25445

Specificity

Recognizes human Fas (CD95, APO-1).

Purification

Purified

Antibody Clonality

Monoclonal