FceRI, alpha (Fc epsilon RI alpha, FCE1A, FCER1A, High Affinity Immunoglobulin epsilon Receptor Subunit alpha, IgE Receptor) (MaxLight 490)
Catalogue Number: F0025-06B2-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 10C204 (9E1) |
| Isotype: | IgG2b |
| Immunogen: | |
| Application: | FC, IF, IP, WB, FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. High affinity Fc receptor for IgE (Fc epsilon R1) plays a central role in the IgE-mediated allergic response. Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Clone 9E1 specifically recognises the extracellular D1 domain of the Fc epsilon R1 alpha chain. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases.
Additional Text
Gene Name
FCER1A
Uniprot ID
P12319
Specificity
Recognizes human Human Fc Epsilon R1, alpha.
Gene ID
2205
Purification
Protein A purified
Antibody Clonality
Monoclonal
F0025-06B2-ML490 Datasheet
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