Doxoves® - STEALTH Liposomal Doxorubicin HCl (4.0mg/mL)

Catalogue Number: F30204B-D-FOR

Manufacturer:	FormuMax
Type:	Liposome
Alias:	F30204A-D, liposomal Doxorubicin, HSPC/CHOL/mPEG2000-DSPE, doxil
Shipping Condition:	Blue Ice
Storage Condition:	2-8°C
Unit(s):	10 ml, 2 ml

Overview

Description

Description: Doxoves® - PEGylated Liposomal Doxorubicin HCl Doxorubicin HCl is loaded into PEGylated liposomes composed of HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) with ammonium gradient by the active loading approach. It is comparable to the commercial product DOXIL®. The liposomes are prepared to very high quality with consistent lot-lot characteristics. Narrow particle size distribution and high drug encapsulation efficiency. Note the high drug concentration (4mg/mL compared to 2 mg/mL for DOXIL®) allows the researchers to perform experiments at higher concentration/doses. Product For Research only and NOT for Human Use Specifications Product code: F30204B-D Lipid composition: HSPC/CHOL/mPEG2000-DSPE (56.2:38.5:5.3 mol/mol) Lipid concentration: 40.0 mM Doxorubicin HCl: 4.0 mg/mL Encapsulation efficiency: > 95% (typically 98%) Loading battery: 250 mM ammonium sulfate Mean particle size: 85 nm (80 - 90 nm) External solution: 10% sucrose, 10 mM histidine, pH 6.5 Shelf-life: 6 months, storage: 2-8 degree C HSPC: hydrogenated phosphatidylcholine (Soy) CHOL: cholesterol mPEG2000-DSPE: 18:0 PEG2000 PE:1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000]

Price

£2,067.00

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