Fibrinogen (Coagulation Factor I) (MaxLight 490)
Catalogue Number: F4200-04D-ML490-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 40F11 |
| Isotype: | IgG1 |
| Immunogen: | Fibrin degradation products. |
| Application: | FLISA |
Description
Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Thrombin converts fibrinogen into fibrin, which is then cross-linked by factor XIII to form a blood clot. Also recognises fibrin degradation products (FDPs), substances that are left behind after a blood clot dissolves. This process, called fibrinolysis, is produced by the action of enzymes such as plasmin on fibrin. One FDP is D-dimer, levels of which can be used to diagnose deep vein thrombosis or pulmonary embolism. fibrinolytic system is also closely linked to the control of inflammation.
Additional Text
Specificity
Recognizes human fibrinogen, a glycoprotein produced in the liver. Fibrinogen is a hexamer, consisting of two sets of three subunits (alpha, beta and gamma).
Purification
Protein A purified
Antibody Clonality
Monoclonal
F4200-04D-ML490 Datasheet
SUPPORT
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PRODUCT
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DELIVERY
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