Fibroblast Activation Protein alpha (FAPa, FAP, 170kD Melanoma Membrane-bound Gelatinase, DKFZP686G13158, DPPIV, EC 3.4.21.-, Integral Membrane Serine Protease, Seprase) (Azide Free) (MaxLight 650)

Catalogue Number: F4208-57H-ML650-USB

Manufacturer:United States Biological
Preservative:Azide-free
Physical state:Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™650.
Type:Monoclonal Primary Antibody - Conjugated
Alias:170 kDa melanoma membrane-bound gelatinase|dipeptidyl peptidase FAP|DPPIV|FAPA|FAPalpha|gelatine degradation protease FAP|integral membrane serine protease|post-proline cleaving enzyme|prolyl endopeptidase FAP|seprase|SIMP|surface-expressed protease
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1E5
Isotype: IgG2a, kappa
Immunogen: Partisl recombinant protein corresponding to aa525-625 of human FAP with a GST tag. MW of tthe GST tag alone is 26kD.
Application: IP, WB, FLISA

Description

Description: MaxLight™650 is a new Far-IR stable dye conjugate comparable to Alexa Fluor™647, DyLight™649, Cy5™ and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (655nm); Emission (676nm); Extinction Coefficient 250,000. The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.

Additional Text

Uniprot ID

Q12884

Gene Name

FAP

Gene ID

2191

Specificity

Recognizes human FAP at ~87kD.

Purification

Purified

Antibody Clonality

Monoclonal