Fibroblast Growth Factor 2, Basic (FGF2b) (MaxLight 550)

Catalogue Number: F4210-21-ML550-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight™550.
Type:	Monoclonal Primary Antibody - Conjugated
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	0.T.49
Isotype:	IgG1, kappa
Immunogen:	Purified bovine brain basic FGF (FGF-2, HBGF-2).
Application:	WB, IHC

Overview
Datasheets

Description

Description: MaxLight™550 is a new Yellow-Green photostable dye conjugate comparable to Alexa Fluor™546, 555, DyLight™549 , Cy3™, TRITC and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (550nm); Emission (575nm); Extinction Coefficient 150,000. FGF basic (FGF2) is a member of the fibroblast growth factor (FGF) family. FGF family members bind heparin and possess broad mitogenic and angiogenic activities. FGF2 is involved in diverse biological processes, such as limb and nervous system development, wound healing, and tumor growth. FGF2 mRNA contains multiple polyadenylation sites, and is alternatively translated from AUG and non-AUG (CUG) initiation codons resulting in five different isoforms with distinct properties. The CUG-initiated isoforms are localized in the nucleus and are responsible for the intracrine effect, whereas, the AUG-initiated form is mostly cytosolic and is responsible for the paracrine and autocrine effects of this FGF.

Additional Text

Uniprot ID

P03969

Specificity

Recognizes bovine Fibroblast Growth Factor 2, Basic (FGF2b). Does not crossreact with bovine acidic FGF. Note: This antibody can cross-react with native and heat-inactivated basic FGF but will not neutralize biological activity. Species Crossreactivity: human, rat, mouse

Purification

Ammonium Sulfate Precipitated; Ion Exchange

Antibody Clonality

Monoclonal

F4210-21-ML550 Datasheet

Price

£1,070.00

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