FLIP, CT (FLICE Inhibitory Protein) (MaxLight 490)

Catalogue Number: F4550-01-ML490-USB

Manufacturer:United States Biological
Physical state:Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Type:Polyclonal Primary Antibody - Conjugated
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Rabbit
Clone:
Isotype: IgG
Immunogen: Peptide at C-terminus of FLIP-L
Application: WB, IHC

Additional Text

Specificity

Recognizes the 55kD FLIPL protein, a FLICE inhibitory protein. FLIP was cloned independently in a number of laboratories and is also known as Casper, I-FLICE, FLAME-1, CASH and CLARP. FLIP has two death effector domains (DEDs) and a caspase-like domain. It interacts with FADD and caspase-8 and -10, potently inhibiting apoptosis by all known death receptors. FLIP exists in a short form (FLIPS) and a long form (FLIPL). Only FLIPL is recognized by this antibody.

Purification

Ion Exchange

Antibody Clonality

Polyclonal