Human Fas/TNFRSF6/CD95 Protein (FAS-HM201)

Catalogue Number: FAS-HM201-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 43.4 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Other Recombinant Protein
Alias:	FASLG receptor; CD95; APT1; FAS1; TNFRSF6; FAS; ALPS1A; APO1; FASTM; FasR
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: CD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TNFR) superfamily. Its cognate ligand, CD95L, is implicated in immune homeostasis and immune surveillance. Mutations in this receptor are associated with a loss of apoptotic signaling and have been detected in an autoimmune disorder called autoimmune lymphoproliferative syndrome (ALPS) type Ia, which shares some clinical features with systemic lupus erythematosus (SLE).

Additional Text

Protein Tag

hFC Tag

Short Description

Recombinant Human Fas/TNFRSF6/CD95 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Asn173.

UniProt ID

P25445-1

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Human Fas Ligand, His Tag at 2Oeg/ml (100Oel/Well) on the plate. Dose response curve for Human Fas, hFc Tag with the EC50 of 87.7ng/ml See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

FAS-HM201 Datasheet

FAS-HM201 MSDS

Price

£153.00

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