Mouse Fas/TNFRSF6/CD95 Protein (FAS-MM201)
Catalogue Number: FAS-MM201-KAT
FAS-MM201 Image
FAS-MM201 Image
FAS-MM201 Image
FAS-MM201 Image
The purity of Mouse Fas is greater than 95% as determined by SEC-HPLC.
FAS-MM201 Image
Mouse Fas on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
FAS-MM201 Image
Immobilized Human Fas Ligand, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Mouse Fas, hFc Tag with the EC50 of 0.25ug/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 43.3 kDa. Due to glycosylation, the protein migrates to 60-65 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | FASLG receptor; CD95; APT1; FAS1; TNFRSF6; FAS; ALPS1A; APO1; FASTM; FasR |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: CD95 (also known as Fas) is a member of the tumor necrosis factor receptor (TNFR) superfamily. Its cognate ligand, CD95L, is implicated in immune homeostasis and immune surveillance. Mutations in this receptor are associated with a loss of apoptotic signaling and have been detected in an autoimmune disorder called autoimmune lymphoproliferative syndrome (ALPS) type Ia, which shares some clinical features with systemic lupus erythematosus (SLE).
Additional Text
Gene Name
FAS
Gene ID
14102
Uniprot ID
P25446
Protein Tag
hFC Tag
Short Description
Recombinant Mouse Fas/TNFRSF6/CD95 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln22-Arg169.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
FAS-MM201 Datasheet
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