Biotinylated Human FGFR1 beta (IIIc) Protein (FGF-HM41CB)

Catalogue Number: FGF-HM41CB-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 25.23 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.
Physical state:Lyophilized
Type:Protein Kinases
Alias:FGFR-1; BFGFR; bFGF-R-1; FLT-2;N-sam; CD331
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug
Application: ELISA, WB

Description

Description: Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment.

Additional Text

Protein Tag

HIS-AviTag™

Uniprot ID

P11362-7

Short Description

Recombinant Biotinylated Human FGFR1 beta (IIIc) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Lys158-Thr355.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Anti-FGFR1 Anitibody at 5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Biotinylated Human FGFR1 beta (IIIc) , His Tag with the EC50 of 0.35Oeg/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

Price
£413.00


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