Biotinylated Human FGFR3 beta (IIIb) Protein (FGF-HM4BBB)

Catalogue Number: FGF-HM4BBB-KAT

Manufacturer:	Kactus
Shelf Life:	12 months
Molecular Weight:	The protein has a predicted MW of 30.5 kDa. Due to glycosylation, the protein migrates to 40-55 kDa based on Bis-Tris PAGE result.
Physical state:	Lyophilized
Type:	Protein Kinases
Alias:	ACH; CD333; CEK; CEK2; EC 2.7.10; FGF R3; FGFR3; HSFGFR3EX; JTK4
Host Cell:	HEK293 cells
Shipping Condition:	RT
Unit(s):	100 ug, 500 ug
Application:	ELISA, WB

Overview
Datasheets

Description

Description: Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.

Additional Text

Protein Tag

HIS-AviTag™

Uniprot ID

P22607-2

Short Description

Recombinant Biotinylated Human FGFR3 beta (IIIb) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Asp127-Gly377.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Biological Activity

Immobilized Biotinylated Human FGFR3 beta (lllb) at 1Oeg/ml (100Oel/Well) on the plate. Dose response curve for Anti-FGFR3 Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA. See testing image for detail.

Endotoxin

Less than 1 EU per µg by the LAL method.

FGF-HM4BBB Datasheet

FGF-HM4BBB MSDS

Price

£413.00

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