Biotinylated Human FGFR1 alpha (IIIc) Protein (FGF-HM4RAB)
Catalogue Number: FGF-HM4RAB-KAT
FGF-HM4RAB Image
FGF-HM4RAB Image
FGF-HM4RAB Image
FGF-HM4RAB Image
Immobilized Biotinylated Human FGFR1 alpha (IIIc), His Tag at 1ug/ml (100ul/well) on the streptavidin precoated plate (5ug/ml). Dose response curve for Anti-FGFR1 Anitibody, hFc Tag with the EC50 of 9.5ng/ml determined by ELISA.
FGF-HM4RAB Image
Biotinylated Human FGFR1 alpha (IIIc) -on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
FGF-HM4RAB Image
The purity of Biotinylated-Human FGFR1 alpha (IIIc) is greater than 95% as determined by SEC-HPLC.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 42 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-BisPAGE result. |
| Physical state: | Lyophilized |
| Type: | Protein Kinases |
| Alias: | FGF R1a; FGFR1 alpha |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Fibroblast growth factors (FGFs) comprise a family of at least eighteen structurally related proteins that are involved in a multitude of physiological and pathological cellular processes, including cell growth, differentiation, angiogenesis, wound healing and tumorgenesis. The biological activities of the FGFs are mediated by a family of type I transmembrane tyrosine kinases which undergo dimerization and autophosphorylation after ligand binding.FGFR1 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system.
Additional Text
Protein Tag
HIS-AviTag™
Uniprot ID
P11362-7
Short Description
Recombinant Biotinylated Human FGFR1 alpha (IIIc) Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Arg22-Glu374.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Anti-FGFR1 Anitibody, hFc Tag at 0.5Oeg/ml (100Oel/Well) on the plate. Dose response curve for Biotinylated Human FGFR1 alpha (IIIc) , His Tag with the EC50 of 25.9ng/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
FGF-HM4RAB Datasheet
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