Biotinylated Human FLT3/Flk-2 Protein (FLT-HM430B)
Catalogue Number: FLT-HM430B-KAT
FLT-HM430B Image
FLT-HM430B Image
FLT-HM430B Image
FLT-HM430B Image
The purity of Biotinylated Human FLT3 is greater than 95% as determined by SEC-HPLC.
FLT-HM430B Image
Biotinylated Human FLT3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
FLT-HM430B Image
Immobilized Biotinylated Human FLT3, His Tag at 1ug/ml (100ul/Well) on streptavidin (5ug/ml) precoated plate. Dose response curve for Human FLT3 Ligand, hFc Tag with the EC50 of 1.2ng/ml determined by ELISA (QC Test).
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 61.20 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Protein Kinases |
| Alias: | CD135; FLK2; STK-1; FLT-3 |
| Host Cell: | CHO Cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: The Flt-3 (fms-like tyrosine kinase) receptor, also named Flk-2 (fetal liver kinase) and Stk-1(stem cell tyrosine kinase) is a member of the class III subfamily of receptor tyrosine kinases that also includes KIT, the receptor for SCF and FMS, the receptor for M-CSF. Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1.
Additional Text
Protein Tag
HIS-AviTag™
Uniprot ID
P36888-1
Short Description
Recombinant Biotinylated Human FLT3/Flk-2 Protein is expressed from CHO with His tag and Avi tag at the C-Terminus.It contains Asn27-Asn541.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
FLT-HM430B MSDS
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