Biotinylated Rat FcRn Protein (FRN-RM401B)
Catalogue Number: FRN-RM401B-KAT
FRN-RM401B Image
FRN-RM401B Image
FRN-RM401B Image
FRN-RM401B Image
Biotinylated Rat FcRn, His Tag- captured on CM5 Chip via Anti-His Antibody can bind Trastuzumab with an affinity constant of 5.08 nM as determined in SPR assay (Biacore T200).
FRN-RM401B Image
Biotinylated Rat FcRn on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
FRN-RM401B Image
The purity of Biotinylated Rat FcRn is greater than 95% as determined by SEC-HPLC.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 33.9 kDa (FCGRT) and 11.63 kDa (B2M). Due to glycosylation, the protein migrates to 45-60 kDa (FCGRT) and 12-14 kDa (B2M) based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Protein - Conjugated |
| Alias: | FcRn alpha chain; FCGRT; FCRN; FCGRT&B2M |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
Description
Description: The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
Additional Text
Protein Tag
HIS-AviTag™
Uniprot ID
P07151, P13599
Gene Name
B2M, FCGRT
Gene ID
24223; 29558
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
Short Description
Recombinant Biotinylated Rat FcRn Protein is expressed from HEK293 with His tag and Avi Tag at the C-terminus of FCGRT.It contains Ala23-Ser298(FCGRT) and Ile21-Met119(B2M).
FRN-RM401B MSDS
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