GLUT 4 (Glucose Transporter 4, Glucose Transporter Type 4 Insulin-responsive, GLUT4, GLUT-4, Solute Carrier Family 2 (Facilitated Glucose Transporter) Member 4, SLC2A4)
Catalogue Number: G3900-50G-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. |
| Type: | Monoclonal Primary Antibody - Unconjugated |
| Shipping Condition: | Blue Ice |
| Unit(s): | 50 ug, 100 ug |
| Host name: | Mouse |
| Clone: | 1F8 |
| Isotype: | IgG1 |
| Immunogen: | Partially purified vesicles containing insulin-responsive glucose transporter 4 |
| Application: | IF, IP, WB, IHC |
Description
Description: Glucose transporter 4 (GLUT4) is an insulin-regulated facilitative glucose transporter found in adipose tissue and striated muscle. When stimulated by insulin, GLUT4 translocates from intracellular stores to the cell surface, facilitating passive diffusion of circulating glucose into muscle and fat cells. GLUT4 is also stimulated to locate to the cell surface by muscle contraction, particularly in cardiac muscle (James et al. 1988). Clone 1F8 has been used successfully to demonstrate the localization of GLUT4 to the basolateral side of ductal structures in the rat submandibular salivary gland in formalin fixed, paraffin embedded material (Cetik et al. 2014).
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene Name
SLC2A4
UniProt ID
P19357
Specificity
Recognizes rat Glucose Transporter 4. Species Crossreactivity: mouse, monkey, rabbit, human. Does not react with canine.
Purification
Protein G purified
Gene ID
25139
Antibody Clonality
Monoclonal
G3900-50G Datasheet
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