Glyceraldehyde 3 Phosphate Dehydrogenase (GAPDH, glyceraldehyde-3-phosphate dehydrogenase, HGNC:4141, G3PD, GAPD, MGC88685) (MaxLight 490)

Catalogue Number: G8140-01L-ML490-USB

Manufacturer:	United States Biological
Physical state:	Supplied as a liquid in PBS, pH 7.2. Labeled with MaxLight™490.
Type:	Monoclonal Primary Antibody - Conjugated
Alias:	aging-associated gene 9 protein\|epididymis secretory sperm binding protein Li 162eP\|G3PD\|GAPD\|glyceraldehyde-3-phosphate dehydrogenase\|HEL-S-162eP\|OCAS, p38 component\|Oct1 coactivator in S phase, 38 Kd component\|peptidyl-cysteine S-nitrosylase GAPDH
Shipping Condition:	Blue Ice
Unit(s):	100 ul
Host name:	Mouse
Clone:	10A7 (4G5)
Isotype:	IgG1
Immunogen:	Human cardiac muscle GADPH.
Application:	IF, IP, WB, IHC, FLISA

Overview
Datasheets

Description

Description: MaxLight™490 is a new Blue-Green photostable dye conjugate comparable to DyLight™488, Alexa Fluor™488 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (491nm); Emission (515nm); Extinction Coefficient 73,000. Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a 36kD multifunctional protein whose main function is to catalyse the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate, in conjunction with inorganic phosphate and nicotinamide adenine dinucleotide (NAD). This reaction is an important energy yielding step in carbohydrate metabolism. GAPDH has also been shown to translocate to the nucleus under a variety of stressors, most of which are associated with oxidative stress, whereby it mediates cell death. A further report has shown that GAPDH binds to several proteins that are responsible for neurodegenerative diseases, such as amyloid precursor protein and Huntingtin.

Additional Text

Gene Name

GAPDH

Specificity

Recognizes human glyceraldehyde-3-phosphate dehydrogenase (GAPDH) at ~36kD. Species Crossreactivity: bovine, porcine, goat, feline, rat, mouse, canine, rabbit and fish

Uniprot ID

P04406

Gene ID

2597

Purification

Protein A purified

Antibody Clonality

Monoclonal

G8140-01L-ML490 Datasheet

Price

£961.00

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