Glycine Receptor Subunit alpha 1 (Glycine Receptor 48kD Subunit, Glycine receptor strychnine-binding subunit, GLRA1) (MaxLight 405)
Catalogue Number: G8167-03-ML405-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, pH 7.2. No preservative and no stabilizing proteins added. Labeled with MaxLight™405. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | glycine receptor 48 kDa subunit|glycine receptor strychnine-binding subunit|glycine receptor subunit alpha-1|HKPX1|STHE |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 ul |
| Host name: | Mouse |
| Clone: | 9G364 |
| Isotype: | IgG |
| Immunogen: | GST-tagged recombinant protein fragment corresponding to amino acids 121-221 of human glycine receptor subunit alpha-1, UniProt accession #P23415. |
| Application: | WB, FLISA |
Description
Description: MaxLight™405 is a new Violet photostable dye conjugate comparable to Alexa Fluor® 405, PacificBlue™, Brilliant™ Violet 421 and offers better labeling efficiency, brighter imaging and increased immunodetection. Absorbance (400nm); Emission (423nm); Extinction Coefficient 32,000. Glycine receptor is a neurotransmitter-gated ion channel. When bound to its ligand, glycine, chloride conductance is increased and consequently inhibits neuronal firing. It is a pentameric receptor composed of alpha and beta subunits and localises to the cell junction, synapse and postsynaptic cell membrane. Defects in GLRA1 cause startle disease (STHE) which is also known as hereditary hyperekplexia or congenital stiff-person syndrome.
Additional Text
Gene Name
GLRA1
Uniprot ID
P23415
Specificity
Recognizes human Glycine Receptor Subunit alpha 1.
Purification
Affinity Purified
Gene ID
2741
Antibody Clonality
Monoclonal
G8167-03-ML405 Datasheet
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