Glycogen Synthase Kinase 3 beta (GSK3b) (Carboxyfluorescein)
Catalogue Number: G8170-50J1-USB
| Manufacturer: | United States Biological |
| Physical state: | Supplied as a liquid in PBS, 0.09% sodium azide. Labeled with Carboxyfluorescein. |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | glycogen synthase kinase-3 beta|GSK-3 beta|GSK3beta isoform|serine/threonine-protein kinase GSK3B |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 Tests |
| Host name: | Rat |
| Clone: | 8H133 |
| Isotype: | IgG2a |
| Immunogen: | Recombinant protein corresponding to Met1-Thr420 from human GSK-3 beta, expressed in E. coli. |
| Application: | FC |
Description
Description: Glycogen Synthase Kinase-3 (GSK-3) is a serine/threonine kinase initially identified as an inhibitor of glycogen synthase. Two isoforms (GSK-3a and GSK-3b) share 85% amino acid identity. GSK-3b, inhibited by phosphorylation at S9 by Akt, is involved in energy metabolism, body pattern formation, and neuronal cell development.
Additional Text
Caution
FOR RESEARCH USE ONLY
Gene ID
2932
Gene Name
GSK3B
Uniprot ID
P49841
Specificity
Recognizes human GSK-3b.
Antibody Clonality
Monoclonal
Purification
Purified by Protein G affinity chromatography from hybridoma culture supernatant. Does not cross-react with recombinant human GSK-3 alpha.
G8170-50J1 Datasheet
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