Cynomolgus GDF15 Protein (GDF-CE115)
Catalogue Number: GDF-CE115-KAT
GDF-CE115 Image
GDF-CE115 Image
GDF-CE115 Image
GDF-CE115 Image
Cynomolgus GDF15 on Bis-Tris PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.
GDF-CE115 Image
Immobilized Cynomolgus GDF15, His Tag at 5 ug/ml (100 ul/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 39.9 ng/ml determined by ELISA (QC Test).
GDF-CE115 Image
Immobilized Cynomolgus GDF15, His Tag at 0.5 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-GDF15 Antibody, hFc Tag with the EC50 of 6.1 ng/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 14.15 kDa. The protein migrates to 15-18 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Cytokines |
| Alias: | GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta; Placental TGF-β; PTGF-β; PTGFBPTGF-β |
| Host Cell: | E.coli |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and that GDF15 was necessary for surviving both bacterial and viral infections, as well as sepsis. The protective effects of GDF15 were largely independent of pathogen control or the magnitude of inflammatory response, suggesting a role in disease tolerance.
Additional Text
Protein Tag
HIS Tag
Uniprot ID
G7PWZ3
Short Description
Recombinant Cynomolgus GDF15 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Arg193-Val308.
Storage Note
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Cynomolgus GDF15, His Tag at 5Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 56.5ng/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
GDF-CE115 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations