Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein (GFL-CM401B)
Catalogue Number: GFL-CM401B-KAT
GFL-CM401B Image
GFL-CM401B Image
GFL-CM401B Image
GFL-CM401B Image
Biotinylated Cynomolgus GFRAL on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
GFL-CM401B Image
Immobilized Cynomolgus GDF15, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 39.9ng/ml determined by ELISA (QC Test).
GFL-CM401B Image
The purity of Biotinylated Cynomolgus GFRAL is greater than 90% as determined by SEC-HPLC.
| Manufacturer: | Kactus |
| Shelf Life: | 12 months |
| Molecular Weight: | The protein has a predicted MW of 40.7 kDa. Due to glycosylation, the protein migrates to 50-70 kDa based on Bis-Tris PAGE result. |
| Physical state: | Liquid |
| Type: | Protein - Conjugated |
| Alias: | GFR alpha-like; GFRAL; GRAL; C6orf144 |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.
Additional Text
Protein Tag
HIS-AviTag™
Accession Number
XP_015304775.2
Short Description
Recombinant Biotinylated Cynomolgus GFRAL/GFR alpha-like Protein is expressed from HEK293 with His tag and Avi tag at the N-Terminus.It contains Gln20-Glu351.
Storage Note
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Cynomolgus GDF15, His Tag at 2Oeg/ml (100Oel/well) on the plate. Dose response curve for Biotinylated Cynomolgus GFRAL, His Tag with the EC50 of 76.3ng/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
GFL-CM401B Datasheet
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