Human GFRAL/GFR alpha-like Protein (GFL-HM401)

Catalogue Number: GFL-HM401-KAT

Manufacturer:Kactus
Shelf Life:12 months
Molecular Weight:The protein has a predicted MW of 40.7 kDa. Due to glycosylation, the protein migrates to 48-62 kDa based on Tris-Bis PAGE result.
Physical state:Lyophilized
Type:Fusion Protein
Alias:GFR alpha-like; GFRAL; GRAL; C6orf144
Host Cell:HEK293 cells
Shipping Condition:RT
Unit(s): 100 ug, 500 ug

Description

Description: GFR alpha -like (GDNF receptor-alpha-like) is a distant member of the GDNFR family of proteins. Mature human GFR alpha-like is a 376 amino acid (aa) type I transmembrane protein. It contains a 333 aa extracellular domain, a 20 aa transmembrane domain and a 23 aa cytoplasmic domain.GFRAL is a brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses.

Additional Text

Gene ID

389400

Gene Name

GFRAL

Uniprot ID

Q6UXV0

Protein Tag

HIS-AviTag™

Short Description

Recombinant Human GFRAL/GFR alpha-like Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ser19-Glu351.

Storage Note

-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Price
£225.00


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