Human GFRA3 Protein (GFR-HM1A3)
Catalogue Number: GFR-HM1A3-KAT
GFR-HM1A3 Image
GFR-HM1A3 Image
GFR-HM1A3 Image
GFR-HM1A3 Image
GFR-HM1A3 Image
The purity of Human GFRA3 is greater than 95% as determined by SEC-HPLC.
GFR-HM1A3 Image
Human GFRA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
GFR-HM1A3 Image
Immobilized Human GFRA3, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human ARTN, hFc Tag with the EC50 of 92.5ng/ml determined by ELISA (QC Test).
GFR-HM1A3 Image
Immobilized Human GFRA3, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-GFRA3 Antibody, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA.
| Manufacturer: | Kactus |
| Shelf Life: | 24 months |
| Molecular Weight: | The protein has a predicted MW of 40.3 kDa. Due to glycosylation, the protein migrates to 50-55 kDa based on Bis-Tris PAGE result. |
| Physical state: | Lyophilized |
| Type: | Other Recombinant Protein |
| Alias: | GDNFR-alpha-3; GFR-alpha-3; GFRA3; GFR alpha3; GPI-linked receptor |
| Host Cell: | HEK293 cells |
| Shipping Condition: | RT |
| Unit(s): | 100 ug, 500 ug |
| Application: | ELISA, WB |
Description
Description: GDNF (glial-cell-line derived neurotrophic factor) is a potent neurotrophic factor for dopaminergic neurons. Neuropsychiatric diseases and their treatments are associated with alterations in the levels of both GDNF and its receptor family (GDNF family receptor alpha or GFRA). GFRA1, GFRA2 and GFRA3 are located in chromosomal regions with suggestive linkage to schizophrenia.
Additional Text
Protein Tag
HIS Tag
Short Description
Recombinant Human GFRA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Asp32-Trp382.
UniProt ID
O60609-1
Storage Note
-20 to -80°C for 24 months as supplied from date of receipt.; -80°C for 3 months after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Biological Activity
Immobilized Human GFRA3, His Tag at 0.2Oeg/ml (100Oel/well) on the plate. Dose response curve for Anti-GFRA3 Antibody, hFc Tag with the EC50 of 7.3ng/ml determined by ELISA. See testing image for detail.
Endotoxin
Less than 1 EU per µg by the LAL method.
GFR-HM1A3 Datasheet
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