Biotinylated Human GLP-1R Protein-Nanodisc (GLP-HM10NB)
Catalogue Number: GLP-HM10NB-KAT
| Manufacturer: | Kactus |
| Shelf Life: | 6 months |
| Molecular Weight: | The protein has a predicted MW of 66.00 kDa. |
| Physical state: | Liquid |
| Type: | Protein - Conjugated |
| Alias: | GLP-1 receptor; GLP-1-R; GLP-1R; GLP1R |
| Host Cell: | HEK293 cells |
| Shipping Condition: | Dry Ice |
| Unit(s): | 100 ug |
Description
Description: Glucagon-like peptide-1 receptor (GLP-1R) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). GLP-1R emerged as an important pharmacological target for addressing T2DM, as it actively contributes to maintaining glucose homeostasis while promoting both β cell proliferation and insulin release. The impact of GLP-1R agonists such as semaglutide extends beyond diabetes control: they play a multifaceted role in regulating blood glucose levels by reducing hunger, moderating food intake, and managing body weight. Notably, GLP-1R agonists inhibit cancer progression in some malignant tumors.
Additional Text
Gene ID
2740
Gene Name
GLP1R
Uniprot ID
P43220
Protein Tag
HIS Tag
Storage Note
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Endotoxin
Less than 1 EU per µg by the LAL method.
Short Description
Recombinant Biotinylated Human GLP-1R Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Ser463.
GLP-HM10NB Datasheet
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PRODUCT
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DELIVERY
we offer free delivery to UK universities and non profit organisations