Syndecan-1 / CD138 antibody [1A3H4]

Catalogue Number: GTX00451-GTX

Manufacturer:GeneTex
Preservative:0.05% Sodium azide
Physical state:Liquid
Type:Monoclonal Primary Antibody - Unconjugated
Alias:syndecan 1 , CD138 , SDC , SYND1 , syndecan
Shipping Condition:Blue Ice
Unit(s): 100 ul
Host name: Mouse
Clone: 1A3H4
Isotype: IgG1
Immunogen: A recombinant fragment of human SDC1 (AA: 28-171) expressed in E. coli.
Application: ELISA, FACS, ICC, IF, IHC-P, WB

Description

Description: The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

6382

Gene Name

SDC1

Uniprot ID

P18827

Molecular Weight

32

Purification

Affinity Purified

Antibody Clonality

Monoclonal

Note

For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption

Application Notes

WB: 1:200-1:1000. ICC/IF: 1:200-1:1000. IHC-P: 1:200-1:1000. FACS: 1:200-1:400. ELISA: 1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.