c-Kit antibody [104D2] (PE-Cy5)

Catalogue Number: GTX00465-09-GTX

Manufacturer:GeneTex
Preservative:15 mM Sodium azide
Molecular Weight:110
Physical state:Liquid
Type:Monoclonal Primary Antibody - Conjugated
Alias:CD117 , CKit , KIT , KIT protooncogene receptor tyrosine kinase , PBT , SCFR , c-Kit , KIT proto-oncogene, receptor tyrosine kinase
Shipping Condition:Blue Ice
Unit(s): 100 tests
Host name: Mouse
Clone: 104D2
Isotype: IgG1
Immunogen: MOLM-1 megakaryocytic cells
Application: FC

Description

Description: This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Additional Text

Gene ID

3815

Gene Name

KIT

Uniprot ID

P10721

Antibody Clonality

Monoclonal

Purification

Size-exclusion Chromatography

Note

For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.

Storage Note

Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.

Application Notes

FCM: 4 µl reagent / 100 µl of whole blood or 10⁶ cells in a suspension. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.