CD16 antibody [3G8] (PE-Cy5)
Catalogue Number: GTX00468-09-GTX
| Manufacturer: | GeneTex |
| Preservative: | 15 mM Sodium azide |
| Molecular Weight: | 29 |
| Physical state: | Liquid |
| Type: | Monoclonal Primary Antibody - Conjugated |
| Alias: | CD16 , CD16A , FCG3 , FCGR3 , FCGR3A , FCGRIII , FCR10 , FCRIII , FCRIIIA , Fc fragment of IgG receptor IIIa , IGFR3 , IMD20 , CD16a |
| Shipping Condition: | Blue Ice |
| Unit(s): | 100 tests |
| Host name: | Mouse |
| Clone: | 3G8 |
| Isotype: | IgG1 |
| Immunogen: | Human neutrophils |
| Application: | FC |
Description
Description: This gene encodes a receptor for the Fc portion of immunoglobulin G, and it is involved in the removal of antigen-antibody complexes from the circulation, as well as other other antibody-dependent responses. This gene (FCGR3A) is highly similar to another nearby gene (FCGR3B) located on chromosome 1. The receptor encoded by this gene is expressed on natural killer (NK) cells as an integral membrane glycoprotein anchored through a transmembrane peptide, whereas FCGR3B is expressed on polymorphonuclear neutrophils (PMN) where the receptor is anchored through a phosphatidylinositol (PI) linkage. Mutations in this gene have been linked to susceptibility to recurrent viral infections, susceptibility to systemic lupus erythematosus, and alloimmune neonatal neutropenia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Additional Text
Gene ID
2214
Gene Name
FCGR3A
Uniprot ID
P08637
Purification
Purified
Antibody Clonality
Monoclonal
Note
For laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. Cy and CyDye are trademarks of GE Healthcare.
Application Notes
*Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Storage Note
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4C. DO NOT FREEZE. Protect from light.
GTX00468-09 Datasheet
SUPPORT
outstanding technical support
PRODUCT
we offer a full product guarantee
DELIVERY
we offer free delivery to UK universities and non profit organisations